Automated Vessel Tortuosity Measurement from Retinal Imaging
June 1, 2025
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1 min read
What problem are we solving?
Vessel tortuosity is a useful biomarker in multiple retinal and systemic conditions, but measurement is often subjective, inconsistent, or requires specialized tools that are not easily reproducible.
What we are building
An automated, open, and reproducible pipeline to:
- preprocess images
- segment/extract vessels (or accept vessel masks)
- compute tortuosity metrics (multiple definitions supported)
- export publication-ready summaries and QC overlays
My role
Primary developer and designer, algorithm selection, implementation, validation strategy, and documentation for open-source release.
Current status
Core pipeline stable; ongoing refinement, validation, and packaging for public release.
Outputs
- Open-source repository (planned)
- Methods write-up and example datasets (planned)
Computational Ophthalmology
Retinal Imaging
Python
Quantitative Biomarkers
Artificial Intelligence
AI

Authors
Ehsan Misaghi
(he/him)
Clinician-Scientist Trainee
Ehsan Misaghi is a Clinician-Scientist Trainee at the University of Alberta working in the intersection of ophthalmology, genetics and artificial intelligence.